Google DeepMind launches AlphaGenome Atlas to predict 9 billion DNA variant effects
Original titleAlphaGenome Atlas: A predictive map of every possible DNA letter change in the human genome
Google DeepMind has introduced AlphaGenome Atlas, a platform with predicted molecular effects for 9 billion single-nucleotide variants in the human genome.
It is free for academic research through a web portal, and the AlphaGenome Variant Impact score condenses predictions from AlphaGenome and AlphaMissense into one number for ranking variants.
The source says collaborators used it to identify variants in unsolved rare disease cases and to find rare non-coding variants linked to traits.
The source details how precomputed variant predictions, a single impact score, and linked feature attributions make genome-wide mutation effects searchable for researchers without coding skills.
Source: Google DeepMind · deepmind.googlePublished · added here